Bharathiar University, CoimbatoreProfessor and Head: Dr. P. Ekambaram
103Total Publications
22Years of Output (1998–2026)
2026Latest Publication Year
1998Earliest Publication Year
2026 5▾
  • Kishore Kumar, R., Aiswarya, J., Manoharan, S., Thiruppathiraja, T., Lakshmipathi, S., Malecki, J. G., ... Perumal, E., and Murugesapandian, B. (2026). Sensing Features and Detection Application of the Bishydroxycoumarin-Diaminopropane Conjugate and the Transmetalation Characteristics of Its Zn (II) Complex. Inorganic Chemistry, 65(24), 13521-13542. View DOI →

  • Deivendran, B., Manoharan, S., and Perumal, E. (2026). A Comprehensive Review on Necroptosis Inducing Phytochemicals for Cancer Therapy: Preclinical Evidence. Phytotherapy Research, 40(6), 3628-3667. View DOI →

  • Manoharan, S., Venkatesan, V., and Perumal, E. (2026). An Integrative Genomic Analysis of Angiogenesis in Hepatocellular Carcinoma: From Canonical Drivers to Emerging Biomarkers. Naunyn-Schmiedeberg's Archives of Pharmacology, 399(7), 10549-10563. View DOI →

  • Manoharan, S., Santhakumar, A., and Perumal, E. (2026). AI-Driven Drug Repurposing Strategies for Hepatocellular Carcinoma: Unlocking New Therapeutic Potential. In Artificial Intelligence in Gastrointestinal Cancers (pp. 239-266). Academic Press. View DOI →

  • Manoharan, S., Govindaraju, I., Venkatesan, V., and Perumal, E. (2026). A Comprehensive Review of Targeting Early-Stage Biomarkers by Small Molecules and Phytochemicals in Hepatocellular Carcinoma. Phytochemistry Reviews, 25(1), 1323-1365. View DOI →

2025 7▾
  • Manoharan, S., and Perumal, E. (2025). Pharmacological Effect of Quinazoline-2, 4 (1H, 3H)-dione Derivatives: A Review. Molecular Diversity, 1-25. View DOI →

  • Babu, S., Sundarraja, V., Manoharan, S., and Perumal, E. (2025). Antioxidant Effect of Esculin and Sulforaphane in Zebrafish Larvae: A Comparative Study. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 297, 110264. View DOI →

  • Deivendran, B., Manoharan, S., and Perumal, E. (2025). Saikosaponin D Modulates STAT3 and c-Myc Expression in MDA-MB-231 Cells: A Comprehensive In Silico and In Vitro Study. Applied Biochemistry and Biotechnology, 197(12), 7821-7843. View DOI →

  • Babu, S., Perumal, E., Sivaraj, M., Majeed, S. A., and Hameed, A. S. S. (2025). Esculin Exerts Nrf2-Mediated Antioxidant Response in DrF Cell Lines and Zebrafish Larvae. Chemico-Biological Interactions, 419, 111638. View DOI →

  • Ottappilakkil, H., Yesudas, G. H., Sreedharan, T., and Perumal, E. (2025). Fisetin Modulates Fluoride Induced Osteochondral Toxicity in Zebrafish Larvae. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 299, 110351. View DOI →

  • Manoharan, S., Murugesan, K., Gunasekaran, S., Vedagiri, H., and Perumal, E. (2025). Quinazoline-2,4(1H,3H)-dione Modulates STAT3 and FOXO3a Signaling in HepG2 Cells. Bioorganic Chemistry, 157, 108304. View DOI →

  • Manoharan, S., and Perumal, E. (2025). Chemotherapeutic Potential of Radotinib Against Blood and Solid Tumors: A Beacon of Hope in Drug Repurposing. Bioorganic Chemistry, 154, 108017. View DOI →

2024 10▾
  • Babu, S., Velmani, N. S., Manoharan, S., and Perumal, E. (2024). Esculin, a Coumarin Glucoside Prevents Fluoride-Induced Oxidative Stress and Cardiotoxicity in Zebrafish Larvae. Environmental toxicology, 40, 636-649. View DOI →

  • Murugesan, S., Balasubramanian, S., and Perumal, E. (2024). Copper Oxide Nanoparticles Induced Reactive Oxygen Species Generation: A Systematic Review and Meta-Analysis. Chemico-Biological Interactions, 405, 111311. View DOI →

  • Manoharan, S., Santhakumar, A., and Perumal, E. (2024). Targeting STAT3, FOXO3a, and Pim-1 Kinase by FDA-Approved Tyrosine Kinase Inhibitor-Radotinib: An in Silico and in Vitro Approach. Archiv der Pharmazie, 257, 2400429. View DOI →

  • Manoharan, S., Ashfaq, S. S., and Perumal, E. (2024). MicroRNAs in Fluorosis Pathogenesis: Impact on Dental, Skeletal, and Soft Tissues. Archives of Toxicology, 98, 3913-3932. View DOI →

  • Balasubramanian, S., and Perumal, E. (2024). Integrated in Silico Analysis of Transcriptomic Alterations in Nanoparticle Toxicity Across Human and Mouse Models. The Science of the Total Environment, 949, 174897. View DOI →

  • Dhakshinamoorthy, V., Vishali, S. P. R., Elumalai, S., and Perumal, E. (2024). Acute Exposure to Environmentally Relevant Concentrations of Pharmaceutical Pollutants Induces Neurobehavioral Toxicity in Zebrafish (Danio rerio). Drug and Chemical Toxicology, 48, 1-14. View DOI →

  • Bhattacharjee, M., Manoharan, S., Sathisaran, U., Tamatam, A., and Perumal, E. (2024). MAO Inhibiting Phytochemicals from the Roots of Glycyrrhiza glabra L. Journal of Biomolecular Structure and Dynamics, 42(8), 3887-3905. View DOI →

  • Manoharan, S., and Perumal, E. (2024). Early-Stage Biomarkers Identification by Integrated Genomic Analysis in Hepatocellular Carcinoma. Medicine in Omics, 12, 100037. View DOI →

  • Balasubramanian, S., Perumal, E., and Santhakumar, K. (2024). Identification of Key Genes and Signalling Pathways in Clear Cell Renal Cell Carcinoma: An Integrated Bioinformatics Approach. Cancer Biomarkers, (Preprint), 1-13. View DOI →

  • Balasubramanian, S., Haneen, M. A., Sharma, G., and Perumal, E. (2024). Acute Copper Oxide Nanoparticles Exposure Alters Zebrafish Larval Microbiome. Life Sciences, 336, 122313. View DOI →

2023 8▾
  • Manoharan, S., Prajapati, K., and Perumal, E. (2023). Natural Bioactive Compounds and FOXO3a in Cancer Therapeutics: An Update. Fitoterapia, 173, 105807. View DOI →

  • Manoharan, S., Saha, S., Murugesan, K., Santhakumar, A., and Perumal, E. (2023). Natural Bioactive Compounds and STAT3 Against Hepatocellular Carcinoma: An Update. Life Sciences, 337, 122351. View DOI →

  • Ottappilakkil, H., Ottoor, A., Manoharan, S., Balasubramanian, M., and Perumal, E. (2023). Fluoride Binding Potential of Selected Phytochemicals: A Pilot Study. Environmental Science and Pollution Research, 30(45), 101888-101895. View DOI →

  • Balasubramanian, S., Duraikannan, V., and Perumal, E. (2023). Toxicogenomic Analysis of Physiologically Important Metals: An Integrated in Silico Approach. Food and Chemical Toxicology, 178, 113895. View DOI →

  • Balasubramanian, S., Rangasamy, S., Vivekanandam, R., and Perumal, E. (2023). Acute Exposure to Tenorite Nanoparticles Induces Phenotypic and Behavior Alterations in Zebrafish Larvae. Chemosphere, 339, 139681. View DOI →

  • Manoharan, S., Prajapati, K., Karthikeyan, T., Vedagiri, H., and Perumal, E. (2023). Virtual Screening of FOXO3a Activators from Natural Product-like Compound Library. Molecular Diversity, 28, 393-1408. View DOI →

  • Anilkumar, A. T., Manoharan, S., Balasubramanian, S., and Perumal, E. (2023). Garcinia gummi-gutta: Phytochemicals and Pharmacological Applications. BioFactors, 49(3), 584-599. View DOI →

  • Manoharan, S., Vedagiri, H., and Perumal, E. (2023). Potent FOXO3a Activators from Biologically Active Compound Library for Cancer Therapeutics: An in Silico Approach. Applied Biochemistry and Biotechnology, 195(8), 4995-5018. View DOI →

2022 7▾
  • Manoharan, S., Deivendran, B., and Perumal, E. (2022). Chemotherapeutic Potential of Saikosaponin D: Experimental Evidence. Journal of Xenobiotics, 12(4), 378-405. View DOI →

  • Balasubramanian, S., and Perumal, E. (2022). A Systematic Review on Fluoride-Induced Epigenetic Toxicity in Mammals. Critical Reviews in Toxicology, 449-468. View DOI →

  • Manoharan, S., and Perumal, E. (2022). Potential Role of Marine Bioactive Compounds Targeting Signaling Pathways in Cancer: A Review. European Journal of Pharmacology, 936, 175330. View DOI →

  • Bhattacharjee, M., Manoharan, S., Deshetty, U. M., and Perumal, E. (2022). Acute Hypobaric Hypoxia Exposure Causes Neurobehavioral Impairments in Rats: Role of Brain Catecholamines and Tetrahydrobiopterin Alterations. Neurochemical Research, 48, 471-486. View DOI →

  • Babu, S., Manoharan, S., Ottappilakkil, H., and Perumal, E. (2022). Role of Oxidative Stress-Mediated Cell Death and Signaling Pathways in Experimental Fluorosis. Chemico-Biological Interactions, 365, 110106. View DOI →

  • Manoharan, S., Balakrishnan, A., Hemamalini, V., and Perumal, E. (2022). Screening of Potent STAT3-SH2 Domain Inhibitors from JAK/STAT Compound Library Through Molecular Dynamics Simulation. Molecular Diversity, 27, 1297-1308. View DOI →

  • Ottappilakkil, H., Babu, S., Balasubramanian, S., Manoharan, S., and Perumal, E. (2022). Fluoride Induced Neurobehavioral Impairments in Experimental Animals: A Brief Review. Biological Trace Element Research, 201, 1214-1236. View DOI →

2021 4▾
  • Sundarraj, K., Raghunath, A., Panneerselvam, L., and Perumal, E. (2021). Fisetin Inhibits Autophagy in HepG2 Cells Via PI3K/Akt/mTOR and AMPK Pathway. Nutrition and cancer, 73(11-12), 2502-2514. View DOI →

  • Balasubramanian, S., and Perumal, E. (2021). Integrated in Silico Analysis for the Identification of Key Genes and Signaling Pathways in Copper Oxide Nanoparticles Toxicity. Toxicology, 463, 152984. View DOI →

  • Thirumurthi, N. A., Raghunath, A., Balasubramanian, S., and Perumal, E. (2021). Evaluation of Maghemite Nanoparticles-Induced Developmental Toxicity and Oxidative Stress in Zebrafish Embryos/Larvae. Biological Trace Element Research, 200(5), 2349-2364. View DOI →

  • Perumal, E., Eswaran, S., Parvin, R., and Balasubramanian, S. (2021). Mitigation of Arsenic Induced Developmental Cardiotoxicity by Ferulic Acid in Zebrafish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 244, 109021. View DOI →

2020 6▾
  • Parthasarathy, A., Vijayakumar, S., Malaikozhundan, B., Thangaraj, M. P., Perumal, E., Murugan, T., ... and Vaseeharan, B. (2020). Chitosan-Coated Silver Nanoparticles Promoted Antibacterial, Antibiofilm, Wound-healing of Murine Macrophages and Antiproliferation of Human Breast Cancer MCF 7 Cells. Polymer Testing, 90, 106675. View DOI →

  • Balasubramanian, S., Raghunath, A., and Perumal, E. (2020). Nanoengineered Biomaterials for Neurodegenerative Disorders. Nanoengineered Biomaterials for Advanced Drug Delivery, 713-734.

  • Balasubramanian, S., Gunasekaran, K., Sasidharan, S., Mathan, V. J., and Perumal, E. (2020). MicroRNAs and Xenobiotic Toxicity: An Overview. Toxicology reports, 7, 583-595. View DOI →

  • Raghunath, A., Nagarajan, R., and Perumal, E. (2020). ZFARED: A Database of the Antioxidant Response Elements in Zebrafish. Current Bioinformatics, 15(5), 415-419.

  • Tharmalingam, B., Mathivanan, M., Mani, K. S., Kaminsky, W., Raghunath, A., Jothi, M., ... and Murugesapandian, B. (2020). Selective Detection of Pyrophosphate Anion by Zinc Ensemble of C3-Symmetric Triaminoguanidine-pyrrole Conjugate and Its Biosensing Applications. Analytica Chimica Acta, 1103, 192-201.

  • Deshetty, U. M., Tamatam, A., Bhattacharjee, M., Perumal, E., Natarajan, G., and Khanum, F. (2020). Ameliorative Effect of Hesperidin Against Motion Sickness by Modulating Histamine and Histamine H1 Receptor Expression. Neurochemical Research, 45(2), 371-384. View DOI →

2019 10▾
  • Panneerselvam L, Raghunath A, Ravi MS, Vetrivel A, Subramaniam V, Sundarraj K., and Perumal E. (2019). Ferulic Acid Attenuates Arsenic Induced Cardiotoxicity in Rats. Biotechnology and applied biochemistry, 67(2), 186-195. View DOI →

  • Sundarraj K, Raghunath A, Panneerselvam L., and Perumal E. (2019). Fisetin, A Phytopolyphenol, Targets Apoptotic and Necroptotic Cell Death in HepG2 Cells. BioFactors, 46(1), 118-135. View DOI →

  • Panneerselvam L, Raghunath A, Sundarraj K., and Perumal E. (2019). Acute Fluoride Exposure Alters Myocardial Redox and Inflammatory Markers in Rats. Molecular biology reports, 46, 6155-6164. View DOI →

  • Balasubramanian S, Raghunath A., and Perumal E. (2019). Role of Epigenetics in Zebrafish development. Gene, 718, 144049. View DOI →

  • Mani R, Balasubramanian S, Raghunath A., and Perumal E. (2019). Chronic Exposure to Copper Oxide Nanoparticles Causes Muscle Toxicity in Adult Zebrafish. Environmental Science and Pollution Research, 27, 27358-27369. View DOI →

  • Panneerselvam, L., Raghunath, A., Sundarraj, K., and Perumal, E. (2019). HO-1/HSP32 and Cardiac Stress Signaling. Heat Shock Proteins in Signaling Pathways, 1877-1254.

  • Velankanni, P., Balasubramanian, S., Raghunath, A., Arfuso, F., Sethi, G., and Perumal, E. (2019). Curcumin as a Potential Therapeutic for Alzheimer's Disease: A Multi-targeted Approach. Medicinal Plants, 79-102.

  • Manickam V, Dhakshinamoorthy V., and Perumal E. (2019). Iron Oxide Nanoparticles Affects Behaviour and Monoamine Levels in Mice. Neurochemical research, 44(7), 1533-1548. View DOI →

  • Raghunath A, Nagarajan R, Sundarraj K, Palanisamy K., and Perumal E. (2019). Identification of Compounds that Inhibit the Binding of Keap1a/Keap1b Kelch DGR Domain with Nrf2 ETGE/DLG Motifs in Zebrafish. Basic & clinical pharmacology & toxicology, 125(3), 259-270. View DOI →

  • Bhattacharjee M., and Perumal E. (2019). Potential Plant-Derived Catecholaminergic Activity Enhancers for Neuropharmacological Approaches: A Review. Phytomedicine, 55, 148-164. View DOI →

2018 11▾
  • Raghunath A, Sundarraj K, Frank A, Sethi G., and Perumal E. (2018). Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance. Cancers, 10(12), 481. View DOI →

  • Raghunath A, Nagarajan R, Sundarraj K, Panneerselvam L., and Perumal E. (2018). Genome-Wide Identification and Analysis of Nrf2 Binding Sites-Antioxidant Response Elements in Zebrafish. Toxicology and Applied Pharmacology, 360, 236-248. View DOI →

  • Raghunath A, Panneerselvam L, Sundarraj K., and Perumal E. (2018). Heat Shock Proteins and Endoplasmic Reticulum Stress. Heat Shock Proteins and Stress, 15, 39-78.

  • Ameeramja J, Raghunath A., and Perumal E. (2018). Tamarind Seed Coat Extract Restores Fluoride-Induced Hematological and Biochemical Alterations in Rats. Environmental Science and Pollution Research, 25(26), 26157-26166. View DOI →

  • Ameeramja J, Kanagaraj VV., and Perumal E. (2018). Protocatechuic Acid Methyl Ester Modulates Fluoride Induced Pulmonary Toxicity in Rats. Food and Chemical Toxicology, 118, 235-244. View DOI →

  • Raghunath A, Sundarraj K, Nagarajan R, Arfuso F, Jinsong B, Kumar AP, Sethi G., and Perumal E. (2018). Antioxidant Response Elements: Discovery, Classes, Regulation and Potential Applications. Redox Biology, 17, 297-314. View DOI →

  • Raghunath, A., Sundarraj, K., Kanagaraj, V. V., and Perumal, E. (2018). Plant Sources as Potential Therapeutics for Alzheimer's Disease. Medicinal Plants, 161-192.

  • Raghunath A., and Perumal E. (2018). Analysis of Lethality and Malformations During Zebrafish (Danio rerio) Development. Teratogenicity Testing, 337-363.

  • Ameeramja J., and Perumal E. (2018). Possible Modulatory Effect of Tamarind Seed Coat Extract on Fluoride-Induced Pulmonary Inflammation and Fibrosis in Rats. Inflammation, 41(3), 886-895. View DOI →

  • Manickam V, Dhakshinamoorthy V., and Perumal E. (2018). Iron Oxide Nanoparticles Induces Cell Cycle-Dependent Neuronal Apoptosis in Mice. Journal of Molecular Neuroscience, 64, 352-362. View DOI →

  • Sundarraj K, Raghunath A., and Perumal E. (2018). A Review on the Chemotherapeutic Potential of Fisetin: In Vitro Evidences. Biomedicine and Pharmacotherapy, 97, 928-940. View DOI →

2017 10▾
  • Manickam V, Periyasamy M, Dhakshinamoorthy V, Panneerselvam L., and Perumal E. (2017). Recurrent Exposure to Ferric Oxide Nanoparticles Alters Myocardial Oxidative Stress, Apoptosis and Necrotic Markers in Male Mice. Chemico-Biological Interaction, 278, 54-64. View DOI →

  • Ameeramja J., and Perumal E. (2017). Protocatechuic Acid Methyl Ester Ameliorates Fluoride Toxicity in A549 Cells. Food and Chemical Toxicology, 109, 941-950. View DOI →

  • Ameeramja J., and Perumal E. (2017). Pulmonary Fluorosis: A Review. Environmental Science and Pollution Research International, 28, 22119-22132. View DOI →

  • Panneerselvam, L., Raghunath, A., and Perumal, E. (2017). Differential Expression of Myocardial Heat Shock Proteins in Rats Acutely Exposed to Fluoride. Cell Stress and Chaperones, 22(5), 743-750. View DOI →

  • Vasanth D, Manickam V., and Perumal E. (2017). Neurobehavioral Toxicity of Iron Oxide Nanoparticles in Mice. Neurotoxicity Research, 32, 187-203. View DOI →

  • Sundarraj K, Raghunath A, Panneerselvam L., and Perumal E. (2017). Iron Oxide Nanoparticles Modulate Heat Shock Proteins and Organ Specific Markers Expression in Mice Male Accessory Organs. Toxicology and Applied Pharmacology, 317, 12-24. View DOI →

  • Raghunath A., and Perumal E. (2017). Metal Oxide Nanoparticles as Antimicrobial Agents: A Promise for the Future. International Journal of Antimicrobial Agents, 49, 137-152. View DOI →

  • Vijayakumar S, Vaseeharan B, Malaikozhundhan B, Gopi N, Perumal E, Pachaiappan R, Velusamy P, Murugan K, Benelli G, Suresh Kumar R., and Suriyanaranayanamoorthy M. (2017). Therapeutic Effects of Gold Nanoparticles Synthesized Using Musa paradisiaca Peel Extract Against Multiple Antibiotic Resistant Enterococcus faecalis Biofilms and Human Lung Cancer Cells (A549). Microbial Pathogenesis, 102, 173-183.

  • Sundarraj K, Manickam V, Raghunath A, Periyasamy M, Viswanathan MP., and Perumal E. (2017). Repeated Exposure to Iron Oxide Nanoparticles Causes Testicular Toxicity in Mice. Environmental Toxicology, 32, 594-608. View DOI →

  • Panneerselvam L, Raghunath A., and Perumal E. (2017). Acute Fluoride Poisoning Alters Myocardial Cytoskeletal and AMPK Signaling Proteins in Rats. International Journal of Cardiology, 229, 96-101. View DOI →

2016 4▾
  • Ganesan S, Anaimalai Thirumurthi N, Raghunath A, Vijayakumar S., and Perumal E. (2016). Acute and Sub-lethal Exposure to Copper Oxide Nanoparticles Causes Oxidative Stress and Teratogenicity in Zebrafish Embryos. Journal of Applied Toxicology, 36, 554-567. View DOI →

  • Raghunath A, Jeyabaskar D, Sundarraj K, Panneerselvam L., and Perumal E. (2016). In silico Prediction of microRNAs on Fluoride Induced Sperm Toxicity in Mice. Food and Chemical Toxicology, 98, 34-49. View DOI →

  • Manju S, Malaikozhundan B, Vijayakumar S, Shanthi S, Jaishabanu A., and Perumal E, Vaseeharan B. (2016). Antibacterial, Antibiofilm and Cytotoxic Effects of Nigella sativa Essential Oil Coated Gold. Microbial Pathogenesis, 91, 129-135. View DOI →

  • Ameeramja J, Panneerselvam L, Govindarajan V, Jeyachandran S, Baskaralingam V., and Perumal E. (2016). Tamarind Seed Coat Ameliorates Fluoride Induced Cytotoxicity, Oxidative stress, Mitochondrial dysfunction and Apoptosis in A549 cells. Journal of Hazardous Materials, 301, 554-565. View DOI →

2015 3▾
  • Panneerselvam L, Govindarajan V, Ammeramja J, Nair HR., and Perumal E. (2015). Single Oral Acute Fluoride Exposure Causes Changes in Cardiac Expression of Oxidant and Antioxidant Enzymes, Apoptotic and Necrotic Markers in Male Rats. Biochimie, 119, 27-35. View DOI →

  • Kanagaraj VV, Panneerselvam L, Govindarajan V, Ameeramja J., and Perumal E. (2015). Caffeic Acid, a Phytopolyphenol Mitigates Fluoride Induced Hepatotoxicity in Rats: A Possible Mechanism. Biofactors, 41, 90-100. View DOI →

  • Raghunath A., and Perumal E. (2015). Micro-RNAs and Their Roles in Eye Disorders. Ophthalmic Research, 53, 69-186.

2014 2▾
  • Subramaniam, A., Shanmugam, M. K., Perumal, E., Li, F., Nachiyappan, A., Kumar, A. P., ... and Sethi, G. (2014). Possible Involvement of Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway in the Initiation and Progression of Hepatocellular Carcinoma. Perspectives in Cancer Prevention-Translational Cancer Research, 73-87.

  • Purushothaman S, Raghunath A, Dhakshinamoorthy V, Panneerselvam L., and Perumal E. (2014). Acute Exposure to Titanium Dioxide (TiO2) Induces Oxidative Stress in Zebrafish Gill Tissues. Toxicological & Environmental Chemistry, 96(6), 890-905. View DOI →

2013 5▾
  • Aruljothi, S., Ser, Y.L., Peramaiyan, R., Kanjoormana, A.M., Perumal E, Feng, L., Muthu, K.S., Kodappully, S.S., Joo-In, P., Kwang, S.A., Kam, M.H., Alan, P.K., and Gautam, S. (2013). An Anthraquinone Derivative, Emodin Sensitized Hepatocellular Carcinoma Cells to TRAIL Induced Apoptosis Through the Induction of Death Receptors and Downregulation of Cell Survival Proteins. Apoptosis, 18, 1175-1187. View DOI →

  • Aruljothi, S., Muthu, K.S., Tina, H.O., Feng, L., Perumal E, Luxi, C., Shireen, V., Taher, A., Shweta, K., Kwang, S.A., Alan, P.K., Kam, M.H., and Gautam, S. (2013). Emodin Inhibits Growth and Induces Apoptosis in an Orthotopic Hepatocellular Carcinoma Model by Blocking Activation of STAT3. British Journal of Pharmacology, 170, 807-821. View DOI →

  • Aruljothi, S., Shanmugam, M.K., Perumal E, Li, F., Nachiyappan, A., Dai, X., Swamy, S.N., Ahn, K.S., Kumar, A.P., Tan, B.K., Hui, K.M., and Sethi, G. (2013). Potential Role of Signal Transducer and Activator of Transcription (STAT3) Signaling Pathway in Inflammation, Survival, Proliferation and Invasion of Hepatocellular Carcinoma. Biochim Biophys Acta, 1835(1), 46-60. View DOI →

  • Manu, K.A., Shanmugam, M.K., Ong, T.H., Aruljothi, S., Siveen, K.S., Perumal E, Samy, R.P., Bist, P., Lim, L.H., Kumar, A.P., Hui, K.M., and Sethi, G. (2013). Emodin Suppresses Migration and Invasion Through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma. PLoS One, 8(3), e57015. View DOI →

  • Perumal E, Vanaja, P., Vimal, G., and Lakshmikanthan, P. (2013). A Brief Review on Experimental Fluorosis. Toxicol Lett, 223, 236-251. View DOI →

2011 1▾
  • Vanaja, P., and Perumal E. (2011). Involvement of Nitric Oxide in Learning and Memory Processes. Indian J. Med Res. 133(5), 471-478.

2010 1▾
  • Perumal E, Namitha, T., Bhuvaneswari, S., Aruljothi, S., Vasanth, D., and Saravanakumar, M. (2010). Therapeutic efficacy of Tamarindus indica (L) to protect against fluoride-induced oxidative stress in the liver of female rats. Fluoride, 43(2), 134-140.

2005 2▾
  • Paul, V., and Perumal E. (2005). Effects of Sodium Nitroprusside, A Nitric Oxide Donor, on Gamma-Aminobutyric Acid Concentration in the Brain and on Picrotoxin-Induced Convulsions in Combination with Phenobarbitone in Rats. Pharmacol Biochem Behav, 80(3), 363-370. View DOI →

  • Paul, V., Reddy, L., and Perumal E. (2005). A Reversal by L-arginine and Sodium Nitroprusside of Ageing-Induced Memory Impairment in Rats by Increasing Nitric Oxide Concentration in the Hippocampus. Indian J. Physiol Pharmacol. 49(2), 179-186.

2004 1▾
  • Paul, V., Reddy, L., and Perumal E. (2004). The Effect of L-arginine on the Memory Impairing Action of Phenobarbitone in Rats that Convulsed After the Injection of Picrotoxin. Indian J. Physiol Pharmacol. 48(2), 191-198.

2003 3▾
  • Paul, V., and Perumal E. (2003). Effect of 7-Nitroindazole Alone and in Combination with Phenobarbitone and Diazepam on Picrotoxin-Induced Convulsions in Rats. Indian J. Physiol Pharmacol. 47(4), 400-406. View DOI →

  • Perumal E., and Paul, V. (2003). Effect of Vitamin D on Chronic Behavioural and Dental Toxicities of Sodium Fluoride in Rats. Fluoride, 36(2), 189-197.

  • Paul, V., Reddy, L., and Perumal E. (2003). Prevention of Picrotoxin Convulsions-Induced Learning and Memory Impairment by Nitric Oxide Increasing Dose of L-arginine in Rats. Pharmacology Biochemistry and Behavior, 75(2), 329-334. View DOI →

2002 1▾
  • Perumal E., and Paul, V. (2002). Modulation of Fluoride in Rats by Calcium Carbonate and by Withdrawal of Fluoride Exposure. Pharmacology and Toxicology, 90(2), 53-58.

2001 1▾
  • Perumal E., and Paul, V. (2001). Calcium Preventing Locomotor Behavioral and Dental toxicities by Decreasing Serum Fluoride Level in Rats. Environmental Toxicology and Pharmacology, 9(4), 141-146.

1998 1▾
  • Paul, V., Perumal E., and Jayakumar, A. R. (1998). Effects of Sodium fluoride on Locomotor Behavior and a Few Biochemical Parameters in Rats. Environmental Toxicology and Pharmacology, 6(3), 187-191.

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