Bharathiar University, CoimbatoreProfessor and Head: Dr. P. Ekambaram

Molecular Toxicology Laboratory

Department of Biotechnology

Research Projects

Ongoing and completed research projects of the Molecular Toxicology Laboratory, supported by national funding agencies and research councils.

3Ongoing projects
11Completed projects
₹3.9 Cr+Cumulative research funding
Supported By
Chief Minister's Research Grant
Tamil Nadu State Council for Science and Technology
Government of India
Indian Council of Medical Research
RUSA
DRDO
DST SERB
TANSCHE
ANRF
ASEAN India

Ongoing Projects

Currently funded research investigating water defluoridation, nanoplastics toxicity and marine bioactive compounds.

Development of Dip and Use Bag for Water Defluoridation Using Tamarindus indica Fruit Shell, Seed Coat and Kernel

INR 33,49,500Jul 2025 – Jul 2028

Molecular Mechanism of Polystyrene Nanoplastics Toxicity in Zebrafish: Genomic and Epigenomic Insights

INR 53,53,680Jul 2025 – Jul 2028

Exploration of Marine Bioactive Compounds for HCC Prevention and Treatment: An in silico, in vitro, and in vivo approach

INR 36,19,584Apr 2025 – Apr 2027

Completed Projects

All 11 completed projects funded by national research councils and agencies.

Targeting miRNAs in Fluorosis Extenuation: Role of Phytochemicals

INR 54,37,526ICMRMar 2022 – Mar 2025

Mitigation of Fluorosis and Fluoride Sensing: An Amalgamation of Biology and Chemistry

INR 60,00,000TANSCHEMay 2021 – May 2024

Novel STAT3 Inhibitors from Plants for Cancer Treatment

INR 14,88,000RUSA–BCTRCJan 2021 – Jun 2023

Dip and Use Bag for Defluoridation and Fluorosis Prevention Using Phytochemicals from Tamarindus indica

INR 7,500TNSCST2022

Identification, Validation and Characterization of Molecular Activators of Keap1/Nrf2/ARE Signaling Pathway in Zebrafish

INR 46,19,000DST–SERB, EEQMar 2019 – Sep 2022

Screening and Analysis of Phytochemicals for Defluoridation of Groundwater

INR 7,00,000RUSA–BUEICHDec 2019 – Jun 2020

Role of Fisetin on Autophagy and Apoptosis in Hepatocellular Carcinoma

INR 11,00,000DST–SERB, EMEQApr 2016 – Mar 2018

Necroptosis in Fluoride Induced Neurotoxicity: Therapeutic Potential of Naringenin via NFκB and Nrf2 Pathways

INR 33,77,625DST–SERBDec 2015 – Nov 2018

Catecholaminergic Activity Enhancer Compounds for Performance Enhancement

INR 20,20,000DRDOJul 2014 – Jun 2018

Therapeutic Efficacy of Enicostema auxilare Extract Against Letrozole Induced PCOS

INR 7,500TNSCST2011

Effects of Tamarind Seed Coat Extract on Fluoride Induced Apoptosis in MRC-9 Cells

INR 13,22,380UGCFeb 2010 – Jan 2013