Bharathiar University, CoimbatoreProfessor and Head: Dr. P. Ekambaram

Understanding toxicity through molecular science

The Molecular Toxicology Laboratory investigates how xenobiotics, fluoride, nanoparticles and other chemical compounds affect cells at molecular and genetic levels.

Research focus

We integrate toxicogenomics, systems toxicology, molecular biology and biochemical approaches to understand toxicant-induced adverse effects.

Molecular toxicology

We study oxidative stress, redox imbalance, mitochondrial dysfunction, inflammation, epigenetic dysregulation and altered cellular signalling, with emphasis on the Keap1/Nrf2/ARE pathway.

Cancer biology

Our group investigates liver, lung, breast and bone cancers using cellular and molecular models, focusing on STAT3, FOXO3a, RANKL and other cancer-associated pathways.

Neurobiology

We explore nitric oxide, monoamines and antioxidant defences in neuronal communication, environmental neurotoxicity, depression and phytochemical-based drug discovery.