Molecular toxicology
We study oxidative stress, redox imbalance, mitochondrial dysfunction, inflammation, epigenetic dysregulation and altered cellular signalling, with emphasis on the Keap1/Nrf2/ARE pathway.
The Molecular Toxicology Laboratory investigates how xenobiotics, fluoride, nanoparticles and other chemical compounds affect cells at molecular and genetic levels.
We integrate toxicogenomics, systems toxicology, molecular biology and biochemical approaches to understand toxicant-induced adverse effects.
We study oxidative stress, redox imbalance, mitochondrial dysfunction, inflammation, epigenetic dysregulation and altered cellular signalling, with emphasis on the Keap1/Nrf2/ARE pathway.
Our group investigates liver, lung, breast and bone cancers using cellular and molecular models, focusing on STAT3, FOXO3a, RANKL and other cancer-associated pathways.
We explore nitric oxide, monoamines and antioxidant defences in neuronal communication, environmental neurotoxicity, depression and phytochemical-based drug discovery.